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Pre-Formulation Scientist Job
Eingestellt von Yoh
Gesuchte Skills: Support, Client
Projektbeschreibung
THE BIG PICTURE - TOP SKILLS YOU SHOULD POSSESS:
- Pre-formulation
- Biopharmaceutical
WHAT YOU'LL BE DOING:
- Monitor solid state forms
- Provide formulations to support PK and pharmacology studies
- Resolve issues of Variable PK/Exposure/Bioavailability
- Develop special formulations for IV and prolonged release
- Review/Request PK profile
- At lead identification and Lead Optimization stages, pre-formulation
- Generate physiochemical properties of the molecule
- Conduct solubility screen in different media, buffers and surfactants to feed into the exposure risk assessment
- Establish formulation for PK screening and pharmacology models to meet exposure requirements
- Complete early crystalline assessment to help in drug substance and drug product development efforts
- Utilize tools such as silico-simulations and gastro plus to provide guidance in formulation changes to resolve variable PK, exposure and bioavailability concerns.
- Probe solution stability at various pH including physiological conditions
- Leads are further optimized and additional knowledge generated to define the toxicology formulation.
- Develop ability assessment
- Salt screening & selection (collaboration with process chemistry and DMPK)
- Preliminary polymorph screening
- Develop formulation for non-GLPMS with greater than 2 years; Ph.D. with greater than 0 year.
WHAT ARE YOU WAITING FOR? APPLY NOW!
RECRUITER:Corrin Pyle
Yoh, a DayJ2W: SCIENTIFIC; MONJOB
TAX TERM: CON_W2J2WMIDATL
Ref:
SFSF: LS
Projektdetails
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Einsatzort:
Summit, Vereinigte Staaten
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Projektbeginn:
asap
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Projektdauer:
Keine Angabe
- Vertragsart:
-
Berufserfahrung:
Keine Angabe
Geforderte Qualifikationen
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Kategorie:
IT Entwicklung, Sonstiges