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Cell and Gene Therapy Technical Development Technician (Advanced)
Eingestellt von Synectics
Gesuchte Skills: Engineering
Projektbeschreibung
JOB RESPONSIBILITIES:
Help with operational start-up of a new process development lab space
Participate in information/tech transfer from external collaborator and implementation of processing technologies (T-cell isolation, activation, viral and nuclease-based genome-engineering, T-cell expansion and cryopreservation, and supporting analytical characterization methods)
Contribute to relevant and impactful innovation programs to enhance manufacturing technologies/capabilities and work processes (such as alternate transfection/cell engineering strategies, media development, disposable/closed production systems and automation) as needed/appropriate.
Work closely with Project Team and key partners - communicate and collaborate effectively to ensure seamless interfaces and interactions with all stakeholder groups
Apply scientific and technical experience to establish safe, high-quality lab practices, and demonstrate strong personal leadership and technical and interpersonal skills
Ensure high-quality, timely documentation in electronic laboratory notebooks and contribute to and Technical Reports as appropriate
SKILLS:
TECHNICAL SKILLS REQUIREMENTS:
PhD degree in Molecular Immunology/Molecular Biology or related field or Chemical Engineering degree (with appropriate Cell and Gene Therapy focus) with 4+ years of postgraduate experience (or MSc with 7+ years) in biotech/biopharma industry (preferably in the development and characterization of manufacturing processes for cell- or gene-based therapies).
Process development for GMP manufacturing of cell- or gene-therapies
T cell molecular biology/engineering and characterization of primary T cells
Molecular virology/engineering and production of recombinant viruses
Mammalian cell genome engineering
Development of analytical methods for characterization of cell-based or gene-therapies - experience with cell-based and flow-cytometry-based assays for characterization of cell populations and/or activity
Cell/Tissue Culture
Projektdetails
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Einsatzort:
South San Francisco, Vereinigte Staaten
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Projektbeginn:
asap
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Projektdauer:
Keine Angabe
- Vertragsart:
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Berufserfahrung:
Keine Angabe
Geforderte Qualifikationen
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Kategorie:
Ingenieurwesen/Technik