Associate Scientist

Summary:

Working within a team setting, the successful applicant will support the development of innovative, robust, efficient, and scalable chemical and biochemical processes and technologies required for the advancement of a diverse and extensive portfolio of bio-conjugate- and polytide-derived Biotherapeutics. The position will focus on process engineering, unit operation scale-up and scale-down, and apply rigorous and engineering principals and approaches to all aspects of conjugate process development and equipment design. This position will support necessary purification activities to produce drug substances with appropriate quality attributes. The candidate will work across process development functions and projects covering a broad portfolio including vaccines, antibody-drug conjugates, therapeutic proteins, and oligonucleotides.

Responsibilities:

- Candidates will work with fellow scientists designing and executing experiments including small-scale studies, and pilot plant and manufacturing studies in a variety of types and scales of equipment from bench top to pilot-scale, and as required, technology transfer and validation in commercial plants.
- Based on the analyses of these studies, these positions will be expected to develop and test new hypotheses to improve fundamental understanding of the chemical and biochemical processes, including bio-conjugation or large and small molecule combinations.
- This position will support process validation, quality by design, regulatory approaches, and quality systems
- This position will also collaborate with the pilot plan and manufacturing staff on experimental studies, clinical manufacturing, and process validation, including work with external contract manufacturing organizations.

SKILLS:

Skills/Qualifications:

- B.S. degree in Chemical/Biochemical Engineering, or equivalent or related field with 0-5 years of industry experience.
- Proven record of delivering results in a fast paced environment and effective communication to project teams.
- Demonstrated ability to drive for results and drive innovative research programs independently.
- Good understanding of chemical engineering/bio-chemical engineering, chemistry/biochemistry and macromolecule analytics.
- Familiarity with recent scientific literature is required.
- Applicants should be self-motivated, organized, and capable of working independently, and in a collaborative environment.
- The successful candidate will possess strong oral and written communication skills.
- Strong analytical and computer skills are required.
- Experience in laboratory automation and LabView software is desired.
- It is highly desirable to have some experience (2-3 years) in process development of Biotherapeutics and in purification technologies such as ultrafiltration and normal filtration.
- Organized and self-motivated plus capable of working independently.
- Manager is looking for someone with more of a chemist background.
- 2+ years experience.
- Manager would like someone with both pharmaceutical and Biotherapeutics experience.
- MS Word.