Virus/Protein Purification Scientist

JOB DUTIES:

- Laboratory and related work (80-90% of time) under daily to weekly supervision
- Work with supervisor to define aim and a plan to achieve that aim, will then execute work following the plan (independently, if familiar with area of work, with guidance if unfamiliar).
- Experimental design in consultation with supervisor, literature review, and increasing emphasis on independent design based on experience.
- Will carry out on-going analysis of data generated and will identify problems
- Will implement necessary changes following discussion with peers/supervisor.
- Will analyze and interpret experimental data, results and methodology used with guidance.
- Will gain skills and experience to be fully conversant with the operation and validation of all items of equipment or IT needed for experimentation, data analysis, storage and data entry.
- Be able to review literature and suggest/apply to technical solutions to bioprocess problems of moderate complexity
- Documentation.
- Daily entry into electronic laboratory notebooks
- Preparation of presentation materials.
- Communication.
- Regular 1:1 communication with supervisor and team colleagues.
- Other colleagues within Vaccine Immunotherapeutics
- Developing communication/presentation skills at internal meetings/poster sessions
- Safe working and regulatory compliance.
- Work safely themselves and be aware of EHS practices of other colleagues.
- Completion of risk assessments, compliance training as required
- Acts independently to maintain a safe and EHS compliant desk and workspace.

POSITION PURPOSE:

- A scientist is required to join Vaccine Immunotherapeutics to develop and support vaccine platform production processes at the research scale.
- The candidate will have solid training and knowledge in mammalian cell culture and virus/protein purification.
- The candidate will be able to independently and proactively apply this knowledge in the design and execution of experimental work, to enable progression of vaccine discovery projects.
- Experience in most or all of the following areas are essential- protein/virus purification using chromatographic techniques (IEX, Affinity & SEC), experience with Unicorn based FPLC systems & tangential flow ultrafiltration and routine protein characterization techniques (SDS-PAGE, Western Blotting, BCA etc)
- In addition, experience in adherent and suspension mammalian cell culture along with transient protein expression is desirable.
- The candidate will be required to work semi-independently and as a member of a team, be accountable for the critical appraisal of their results and present them for review, at specific project milestones.
- The role is laboratory based, and a major emphasis is placed upon laboratory training to increase the scope of practical abilities, as well as the theory behind such practical work.

TRAINING/EDUCATION:

- BSs or MSc in biological sciences or biochemical/chemical engineering
- At least 1 year working in a laboratory in an academic or industrial setting

PREFERRED:

- Experience in most or all of the following areas are essential- protein/virus purification using chromatographic techniques, experience with Unicorn based FPLC systems & tangential flow ultrafiltration
- In addition, experience in adherent and suspension mammalian cell culture along with transient protein expression is desirable.
- MS Word