Scientist

SCIENTIST Job Location: Tarrytown

AUTO REQ ID 347BR
JOB POSTING TITLE: Scientist
LOCATION: Tarrytown
JOB SUMMARY AND ESSENTIAL FUNCTIONS:

If you are looking for an uncommon opportunity -- a chance to join an organization known for its scientific excellence in the research and development of pharmaceuticals -- it's time to consider Regeneron.

Regeneron is a fully integrated biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron markets three products in the United States, EYLEA® (aflibercept) Injection, ZALTRAP® (ziv-aflibercept) Injection for Intravenous Infusion, and ARCALYST® (rilonacept) Injection for Subcutaneous Use; ZALTRAP is co-commercialized with Sanofi. Phase 3 studies are in progress with EYLEA in two additional indications and with product candidates sarilumab and REGN727. Regeneron has active research and development programs in many disease areas, including ophthalmology, inflammation, cancer, and hypercholesterolemia.

We are looking for a Scientist with a background in protein mass spectrometry to join the Analytical Chemistry group of Regeneron located at Tarrytown, NY. The candidate will focus on applying the state-of-the-art mass spectrometry technology to conduct biochemical characterization of Regeneron's antibody-based therapeutic proteins. The candidate will be involved in developing analytical methods for protein primary structure analysis, carbohydrate profiling, protein charge variants analysis, and post-translational modifications (PTMs) identification and related variants from all stages of the antibody drug development. The candidate will also be involved in developing innovative mass spectrometry technologies to support the R
- Conducts analytical experiments on therapeutic proteins, and analyzes mass spectrometry data to elucidate the quality attributes of therapeutic protein candidates and/or products;
- Conducts analytical methods qualification to support the late-stage therapeutic protein development programs;
- Documents experiments, results and findings in laboratory notebook; presents work at the group and department meetings; participates in the writing of technical reports, SOPs, and analytical method protocols etc.
- Provides the data in a quality presentation form (graphs, figures, tables, etc.) to support regulatory submissions and peer-reviewed publications;