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Research & Development Scientist - Pharmaceutical
Eingestellt von Elevate Direct
Gesuchte Skills: Design, Engineering
Projektbeschreibung
RESEARCH & DEVELOPMENT SCIENTIST/BEERSE, BELGIUM/12 MONTHS CONTRACT/53 EUR PER HR
As a Scientist, your overall mission is to design, validate and implement automated high output workflows in the Janssen R&D biopharmaceutical platform. You will focus on scientific innovations to strengthen our knowledge of the biopharmaceutical properties of the drug substance and drug product, ensuring optimal in vivo performance.
YOUR FUNCTION:
Implementation of (semi-)automated high-output in vitro workflows in the Janssen R&D biopharmaceutical platform to understand and predict the gastro-intestinal absorption potential of new compounds across stages of development.
Design, coordinate, execute and report experimental work related to Biopharmaceutics and Physiology Based Pharmacokinetic (PBPK) modelling in support of drug product development.
Continuously improve existing workflows based on in silico needs and in vivo performance.
Participate in the evaluation of new analytical techniques in the area of biorelevant testing and keep up to date with scientific innovations.
Build and maintain strong relationship with key stakeholders including Discovery Sciences, Clinical Pharmacology, Drug Product Development and Analytical Development.
Work in a multidisciplinary team of researchers, internally as well as externally.
YOUR PROFILE:
Doctorate (Ph.D.) in Biopharmaceutics, Pharmaceutical Sciences, Biology, Engineering or related science with relevant experience in biopharmaceutics.
Hands on experience with biopharmacy related in vitro techniques (eg solubility, dissolution, precipitation, solid state characterization, permeability ).
Knowledge and experience in working with down scaled and automated high-throughput experimentation and characterization platforms
Knowledge of and strong interest in API physico-chemistry, solid state, drug absorption principles, formulation optimization, pharmacokinetics and mechanistic design.
Understanding of the concepts behind PBPK modelling (Gastroplus/Simcyp) and in vitro biopharmaceutics (eg solubility, biorelevant dissolution, particle characterization, solid state characteristics ).
Like to work in the lab and able to perform experiments in state-of-the-art laboratories including using automated platforms
Highly motivated, with excellent organizational, interpersonal, communication, and collaborative skills.
Fluent English (both spoken and written) with excellent scientific writing skills.
Team player, dynamic, stress resistant, innovative and flexible
THE COMPANY
Johnson & Johnson is an American multinational medical devices, pharmaceutical and consumer packaged goods manufacturer founded in 1886.
This job with Johnson & Johnson is a temporary assignment and is being managed by Kelly Services on behalf of Johnson & Johnson. Successful candidates will be placed at the Johnson & Johnson assignment and managed by Kelly Services
If you match these requirements, please apply in the normal way. Elevate will send you an email, please open, click and action that email and your application will be visible to the hiring organisation directly.
As a Scientist, your overall mission is to design, validate and implement automated high output workflows in the Janssen R&D biopharmaceutical platform. You will focus on scientific innovations to strengthen our knowledge of the biopharmaceutical properties of the drug substance and drug product, ensuring optimal in vivo performance.
YOUR FUNCTION:
Implementation of (semi-)automated high-output in vitro workflows in the Janssen R&D biopharmaceutical platform to understand and predict the gastro-intestinal absorption potential of new compounds across stages of development.
Design, coordinate, execute and report experimental work related to Biopharmaceutics and Physiology Based Pharmacokinetic (PBPK) modelling in support of drug product development.
Continuously improve existing workflows based on in silico needs and in vivo performance.
Participate in the evaluation of new analytical techniques in the area of biorelevant testing and keep up to date with scientific innovations.
Build and maintain strong relationship with key stakeholders including Discovery Sciences, Clinical Pharmacology, Drug Product Development and Analytical Development.
Work in a multidisciplinary team of researchers, internally as well as externally.
YOUR PROFILE:
Doctorate (Ph.D.) in Biopharmaceutics, Pharmaceutical Sciences, Biology, Engineering or related science with relevant experience in biopharmaceutics.
Hands on experience with biopharmacy related in vitro techniques (eg solubility, dissolution, precipitation, solid state characterization, permeability ).
Knowledge and experience in working with down scaled and automated high-throughput experimentation and characterization platforms
Knowledge of and strong interest in API physico-chemistry, solid state, drug absorption principles, formulation optimization, pharmacokinetics and mechanistic design.
Understanding of the concepts behind PBPK modelling (Gastroplus/Simcyp) and in vitro biopharmaceutics (eg solubility, biorelevant dissolution, particle characterization, solid state characteristics ).
Like to work in the lab and able to perform experiments in state-of-the-art laboratories including using automated platforms
Highly motivated, with excellent organizational, interpersonal, communication, and collaborative skills.
Fluent English (both spoken and written) with excellent scientific writing skills.
Team player, dynamic, stress resistant, innovative and flexible
THE COMPANY
Johnson & Johnson is an American multinational medical devices, pharmaceutical and consumer packaged goods manufacturer founded in 1886.
This job with Johnson & Johnson is a temporary assignment and is being managed by Kelly Services on behalf of Johnson & Johnson. Successful candidates will be placed at the Johnson & Johnson assignment and managed by Kelly Services
If you match these requirements, please apply in the normal way. Elevate will send you an email, please open, click and action that email and your application will be visible to the hiring organisation directly.
Projektdetails
Geforderte Qualifikationen
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Kategorie:
Medien/Design, Ingenieurwesen/Technik