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Postdoctoral Scholar

Eingestellt von Penn State College of Medicine

Projektbeschreibung

A Postdoctoral Scholar position is immediately available in the laboratory of Dr. Channe Gowda at the Penn State College of Medicine. Will express full length VAR2CSA in human HEK 293 cells, purify the proteins in amount sufficient for the proposed studies. He/She will select and maintain C4S- adherent parasites and perform IRBC adhesion and inhibition studies to validate the inhibitors identified by high throughput screening. He/She will also prepare photoaffinity-tagged C4S oligosaccharides and characterize the C4S binding site in VAR2CSA by using tagged oligosaccharides and mass spectrometry, prepare florescent conjugates of oligosaccharides for C4S binding analysis, perform HTS screening of libraries to identify inhibitors VAR2CSAbinding to C4S, and validate the identified inhibitors. He/she will also organize and interpret data, and prepare manuscripts. This position if funded for one year from date of start with possibility of re-funding.

Projektdetails

  • Vertragsart:

    Contract

  • Berufserfahrung:

    Keine Angabe

Geforderte Qualifikationen

  • Kategorie:

    Sonstiges

Penn State College of Medicine