Post-Doctoral Fellowship in Alzheimer's Disease Biomarkers

The National Institute on Aging (NIA), a major research component of the National Institutes of Health (NIH) and the Department of Health and Human Services (HHS), is recruiting a postdoctoral fellow with interests in biomarker discovery for Alzheimer's disease (AD) in the Unit of Clinical and Translational Neuroscience, within the Laboratory of Behavioral Neuroscience.
This research represents an exciting new initiative within the NIA intramural research program (IRP) to discover biologically relevant biomarkers that accurately reflect AD neuropathology and identify potential targets for effective disease modification/intervention.

In these studies, we use a variety of 'Omics' approaches in both blood and brain tissue including proteomics, metabolomics and protein array techniques (for eg: Association of plasma clusterin concentration with severity, pathology and progression in Alzheimer's disease. ARCHIVES OF GENERAL PSYCHIATRY 67(7): 739-748 (2010); Proteome-based plasma markers of brain amyloid beta deposition in non-demented older individuals. JOURNAL OF ALZHEIMER'S DISEASE 22(4):1099-109 (2010); Plasma biomarkers of brain atrophy in Alzheimer's disease. PLoS ONE 6(12):e28527 (2011); Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment. NEUROIMAGE 59(1):212-7 (2012)

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