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Laboratory Technician Bioanalytics and MS (m/f)
Eingestellt von Hays aus Mannheim, Universitätsstadt
Projektbeschreibung
REFERENZNUMMER:
342855/11
IHRE AUFGABEN:
-Sample work-up for analytics from both, biological samples and samples from synthetic working chemists
-Development and validation of analytical methods with HPLC and HPLC-MS for the analytics of biological samples for pre-clinical and clinical studies
-Use and maintenance of chromatographic devices (pumps, auto samplers, valves)
-Use and maintenance of single and triple-quadruple mass spectrometer (calibration with reference compounds, tuning of the instrument for new compounds)
-Development of quantification methods for compounds of interest in biological samples from both in-vivo (plasma, urine etc.) and in-vitro studies, including sample work-up, LC-MS/MS analysis, evaluation of the data and editing of the results
-Development of quantification and scanning methods for metabolite identification
-Metabolic stability with plasma, microsomes and hepatocytes of different species to predict hepatic clearance and phase II metabolism; sample preparation and analysis
-Daily laboratory management
-Development of automated solutions for samples preparation and work-up (Hamilton Liquid Handler)
IHRE QUALIFIKATIONEN:
-Education in Chemistry, Pharmacy or equivalent degree FH, HTL
-Experience in analytical standard techniques for sample preparation and separation
-Experience in mass spectrometry
-Knowledge in chromatographic separation
-Method development HPLC-MS/MS
-Experience in a GLP environment
-Good knowledge in English (oral/written)
-Knowledge of method validation
WEITERE QUALIFIKATIONEN:
Laboratory employee
342855/11
IHRE AUFGABEN:
-Sample work-up for analytics from both, biological samples and samples from synthetic working chemists
-Development and validation of analytical methods with HPLC and HPLC-MS for the analytics of biological samples for pre-clinical and clinical studies
-Use and maintenance of chromatographic devices (pumps, auto samplers, valves)
-Use and maintenance of single and triple-quadruple mass spectrometer (calibration with reference compounds, tuning of the instrument for new compounds)
-Development of quantification methods for compounds of interest in biological samples from both in-vivo (plasma, urine etc.) and in-vitro studies, including sample work-up, LC-MS/MS analysis, evaluation of the data and editing of the results
-Development of quantification and scanning methods for metabolite identification
-Metabolic stability with plasma, microsomes and hepatocytes of different species to predict hepatic clearance and phase II metabolism; sample preparation and analysis
-Daily laboratory management
-Development of automated solutions for samples preparation and work-up (Hamilton Liquid Handler)
IHRE QUALIFIKATIONEN:
-Education in Chemistry, Pharmacy or equivalent degree FH, HTL
-Experience in analytical standard techniques for sample preparation and separation
-Experience in mass spectrometry
-Knowledge in chromatographic separation
-Method development HPLC-MS/MS
-Experience in a GLP environment
-Good knowledge in English (oral/written)
-Knowledge of method validation
WEITERE QUALIFIKATIONEN:
Laboratory employee
Projektdetails
Geforderte Qualifikationen
-
Kategorie:
Sonstiges