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Cell Line Engineering Scientist

Eingestellt von Synectics

Gesuchte Skills: Engineering

Projektbeschreibung

SUMMARY

- Assist in ongoing monoclonal antibody development efforts.
- Antibodies for biotherapeutics target validation and immunohistochemistry assay will be developed using accelerated monoclonal antibody development technologies.
- This position requires experience the development of monoclonal antibodies by standard rodent hybridoma procedures, experience protein immunogen preparation from mammalian cells, or purification and characterization of antibodies.
- This scientist will also be expected to complete documentation of all experiments and communicate results in a number of different formats including in formal presentations.

POSITION RESPONSIBILITIES:

- Generating cell-based immunogens for rodent immunization and ensure quality of these reagents
- Assist in monitor immunization process through custom ELISA assays
- Complete hybridoma selection and screening using developed ELISA assay
- Inventory and expand stable clones for monoclonal antibody production
- Complete small scale antibody purification for screens and characterization.
- Present the findings of antibody development efforts and collaborate with immunohistochemistry and biotherapeutic development teams to generate monoclonal antibodies for initial validation efforts."

SKILLS:

BASIC QUALIFICATIONS:

- Masters in Biology, Biochemistry, Immunology or other related field with laboratory research experience and specific expertise in antibody development and characterization.
- Must have excellent communication and organizational and skills and the ability to work in multidisciplinary teams.
- Laboratory experience in cell engineering, plasmid preparations, antibody characterization, antibody engineering, ELISA assays.
- Additional experience in the production lentiviral engineered cell lines, standard cell line lymphocyte or hybridoma cell culture, and ELISA screening is required.

PREFERRED QUALIFICATIONS:

- Knowledge of cell engineering, advanced hybridoma screening technologies, B cell isolation and characterization, ELISA assay screens and liquid handling-mediated assay automation.
- Immunoassays (RIA, ELISA)

Projektdetails

  • Einsatzort:

    Pearl River, Vereinigte Staaten

  • Projektbeginn:

    asap

  • Projektdauer:

    Keine Angabe

  • Vertragsart:

    Contract

  • Berufserfahrung:

    Keine Angabe

Geforderte Qualifikationen

  • Kategorie:

    Ingenieurwesen/Technik

  • Skills:

    engineering

Synectics