Vakante Jobangebote finden Sie unter Projekte.
Cell Line Engineering Scientist
Eingestellt von Synectics
Gesuchte Skills: Engineering
Projektbeschreibung
- Assist in ongoing monoclonal antibody development efforts.
- Antibodies for biotherapeutics target validation and immunohistochemistry assay will be developed using accelerated monoclonal antibody development technologies.
- This position requires experience the development of monoclonal antibodies by standard rodent hybridoma procedures, experience protein immunogen preparation from mammalian cells, or purification and characterization of antibodies.
- This scientist will also be expected to complete documentation of all experiments and communicate results in a number of different formats including in formal presentations.
POSITION RESPONSIBILITIES:
- Generating cell-based immunogens for rodent immunization and ensure quality of these reagents
- Assist in monitor immunization process through custom ELISA assays
- Complete hybridoma selection and screening using developed ELISA assay
- Inventory and expand stable clones for monoclonal antibody production
- Complete small scale antibody purification for screens and characterization.
- Present the findings of antibody development efforts and collaborate with immunohistochemistry and biotherapeutic development teams to generate monoclonal antibodies for initial validation efforts."
SKILLS:
BASIC QUALIFICATIONS:
- Masters in Biology, Biochemistry, Immunology or other related field with laboratory research experience and specific expertise in antibody development and characterization.
- Must have excellent communication and organizational and skills and the ability to work in multidisciplinary teams.
- Laboratory experience in cell engineering, plasmid preparations, antibody characterization, antibody engineering, ELISA assays.
- Additional experience in the production lentiviral engineered cell lines, standard cell line lymphocyte or hybridoma cell culture, and ELISA screening is required.
PREFERRED QUALIFICATIONS:
- Knowledge of cell engineering, advanced hybridoma screening technologies, B cell isolation and characterization, ELISA assay screens and liquid handling-mediated assay automation.
- Immunoassays (RIA, ELISA)
Projektdetails
-
Einsatzort:
Pearl River, Vereinigte Staaten
-
Projektbeginn:
asap
-
Projektdauer:
Keine Angabe
- Vertragsart:
-
Berufserfahrung:
Keine Angabe
Geforderte Qualifikationen
-
Kategorie:
Ingenieurwesen/Technik