Cell Biologist

SUMMARY:

- This is a primarily a laboratory based role.
- The individual will be required to work with moderate supervision, as part of a team and individually, and will be accountable for the delivery and critical appraisal of their results.

RESPONSIBILITIES:

- Laboratory and related work (80-90% of time) under daily to weekly supervision.
- Work with supervisor to define aim of experiments and a plan to achieve that aim in a given time frame, will then execute work following the plan (independently, if familiar with area of work, with guidance if unfamiliar).
- Will carry out on-going analysis of data generated and will identify problems.
- Will implement necessary changes following discussion with peers/supervisor.
- Will analyze and interpret experimental data, results and methodology used with appropriate guidance.
- Will gain skills and experience to be fully conversant with the operation and validation of all items of equipment or IT needed for experimentation, data analysis, storage and data entry.
- Documentation: Write up laboratory notebooks regularly in compliance with GSP and internal policies. Preparation of presentation materials.
- Contribute to writing of eg SOPs, study reports and protocols.
- Communication: Regular communication with supervisor and team members (1:1 and group meetings). Communication/presentation at internal meetings.
- Safe working and regulatory compliance: Work safely themselves. Completion of risk assessments, compliance with PGRD procedures.
- Will recognize risks (own and others), within own area of expertise.
- Intervene or take action, where appropriate.

SKILLS:

EDUCATION:

- B.Sc. or M.Sc. in life sciences, preferably in cell biology/virology/immunology.
- With at least 1 year working in a laboratory in either an academic or (preferably) industrial setting.
- Experience in one or more of the following areas is essential -
- Maintenance of mammalian cell lines in culture (both adherent and suspension culture)
- Plate-based cellular assays relevant to immunology and/or virology
- Experience in one or more of the following areas is preferred:

96-/384-well plate based assays
virus infectivity and/or neutralization assays
qRT-PCR to measure total virus load
ELISA-based techniques to measure antibody responses
transient transfection of mammalian cells.

MOST CRITICAL SKILLS:
Maintenance of adherent and suspension cell lines in culture (ESSENTIAL)
Plate-based cellular assays relevant to immunology and/or virology
qRT-PCR

ADDITIONAL SKILLS:

- Candidate MUST have experience with MAMMALIAN cell lines.
- Must also have undergraduate degree.