Cell and Gene Therapy Technical Development Technician (Intermediate)

Summary:
We are seeking a highly motivated, results-oriented, self-starter who demonstrates personal accountability for outcomes and thrives on increasing levels of responsibility, to help with the start-up of a new facility and participate in the development and characterization of manufacturing processes for T-cell therapies.

Job Responsibilities:
Help with operational start-up of a new process development lab space
Participate in information/tech transfer from external collaborator and implementation of processing technologies (T-cell isolation, activation, genome-engineering, expansion, cryopreservation, and supporting associated analytical characterization methods)
Contribute to relevant and impactful innovation programs to enhance manufacturing technologies/capabilities and work processes (such as alternate transfection/cell engineering strategies, media development, disposable/closed production systems and automation) as needed/appropriate.
Work closely with Project Team and key partners - communicate and collaborate effectively to ensure seamless interfaces and interactions with all stakeholder groups
Apply scientific and technical experience to establish safe, high-quality lab practices, and demonstrate strong personal leadership and technical and interpersonal skills
Ensure high-quality, timely documentation in electronic laboratory notebooks and contribute to and Technical Reports as appropriate.

SKILLS:
Technical Skills Requirements:
Degree in Molecular Immunology/Molecular Biology or related field or Chemical. Engineering degree (with appropriate Cell and Gene Therapy focus) with relevant laboratory experience (BSc +5 years/MSc +3 years), preferably in biotech/biopharma industry.
Process development for manufacturing of cell- or gene-therapies
T cell molecular biology/engineering and characterization of primary T cells
Molecular virology/engineering and production of recombinant viruses
Mammalian cell genome engineering
Development of analytical methods for characterization of cell-based or gene-therapies - experience with cell-based and flow-cytometry-based assays for characterization of cell populations and/or activity
Cell/Tissue Culture